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Anti-HIF-1 alpha Rabbit pAb

規(guī)格:50μL/100μL

貨號(hào):PN0066

價(jià)格:1350元/50μL 、2200元/100 μL

產(chǎn)品特性



1746606367160578.pnghif-1α 一抗-產(chǎn)品說(shuō)明書(shū)


抗體來(lái)源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Human,Rat (predicted: Mouse,Dog,Pig,Cow,Rabbit)

產(chǎn)品應(yīng)用

WB=1:500-2000,

IHC-P=1:100-500,

IHC-F=1:100-500,

ICC=1:100,

IF=1:100-500,

Flow-Cyt=1μg/Test,

ELISA=1:5000-10000
not yet tested in other applications.optimal dilutions/concentrations shoμLd be determined by the end user.

理論/實(shí)際分子量

92kDa / 110kDa

細(xì)胞定位

細(xì)胞核 細(xì)胞漿 

性    狀

Liquid

濃    度

1mg/ml

免 疫 原

KLH conjugated synthetic peptide derived from middle of human HIF-1 Alpha: 341-450/826 

亞    型

IgG

純化方法

affinity purified by Protein A

Uniprot ID

Q16665

緩 沖 液

0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.

保存條件

Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

背景

Hypoxia-inducible factor-1 (HIF1) is a transcription factor found in mammalian cells cμLtured under reduced oxygen tension that plays an essential role in cellμLar and systemic homeostatic responses to hypoxia. HIF1 is a heterodimer composed of an alpha subunit and a beta subunit. The beta subunit has been identified as the aryl hydrocarbon receptor nuclear translocator(ARNT). This gene encodes the alpha subunit of HIF-1. Overexpression of a natural antisense transcript (aHIF) of this gene has been shown to be associated with nonpapillary renal carcinomas. Two alternative transcripts encoding different isoforms have been identified.