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Anti-HO-1 /HMOX1 Rabbit pAb

規(guī)格：50μL/100μL

貨號：PN0151

價格：1350元/50 μL 、2200元/100 μL

產(chǎn)品特性


1746606367160578.pngHO-1 (HMOX1)一抗-產(chǎn)品說明書


抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應

Human, Mouse, Rat (predicted: Human, Mouse, Rat, Pig, Monkey, Chicken, Bovine, Goat)

產(chǎn)品應用

WB : 1:1000-1:6000

IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

IHC : 1:50-1:500

IF-P : 1:50-1:500

FC (INTRA) : 0.40 ug per 10^6 cells in a 100 μl suspension

理論/實際分子量

28kDa/33kDa 

細胞定位

Endoplasmic reticμLum membrane

性    狀

Liquid

濃    度

800ug/ml

免 疫 原

HO-1/HMOX1 fusion protein Ag1190

亞    型

IgG

純化方法

Antigen affinity purification

Uniprot ID

P09601

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

注意事項

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

Heme oxygenase (HMOX1) catalyzes the first and rate-limiting step in the degradation of heme to yield equimolar quantities of biliverdin Ixa, carbon monoxide (CO), and iron. It has 3 isoforms: HO-1 is highly inducible, whereas HO-2 and HO-3 are constitutively expressed (PMID:10194478). Heme oxygenase-1 (HO-1) is expressed in many tissues and vascμLar smooth muscle cells, and endothelial cells and has been identified as an important endogenous protective factor induced in many cell types by various stimμLants, such as hemolysis, infiammatory cytokines,oxidative stress, heat shock, heavy metals, and endotoxin. And the fμLl-length HO-1 is very unstable and susceptible to truncation that generates an inactive, soluble form (28 kDa)