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Anti-Carbonic Anhydrase 9（CA9） Rabbit pAb

規(guī)格：50μL/100μL

貨號：PN0152

價格：1350元/50 μL 、2200元/100 μL

產(chǎn)品特性


1746606367160578.pngCarbonic Anhydrase 9（CA9）一抗-產(chǎn)品說明書

抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Human, Mouse, Rat

產(chǎn)品應(yīng)用

WB :1: 500 - 1:2000

IHC-P: 1:50 - 1:200

IF/ICC: 1:50 - 1:200

理論/實際分子量

50kDa / 58kDa 

細(xì)胞定位

Cell membrane, Cell projection, Nucleus, Single-pass type I membrane protein, microvillus membrane, nucleolus

性    狀

Liquid

濃    度


免 疫 原

Recombinant fusion protein containing a sequence corresponding to amino acids 52-151 of human Carbonic Anhydrase 9

亞    型

IgG

純化方法

Affinity purification

Uniprot ID

Q16790

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

注意事項

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

背景

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellμLar localization. CA IX is a transmembrane protein and is one of only two tumor-associated carbonic anhydrase isoenzymes known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12.