規(guī)格：50μL/100μL
貨號(hào)：PN0068
價(jià)格：1350元/50 μL ,2200元/100 μL
抗體來(lái)源 | Rabbit |
克隆類型 | Monoclonal |
交叉反應(yīng) | Human,Mouse,Rat,Hamster |
產(chǎn)品應(yīng)用 | WB 1:1000~1:2000 IHC 1:50~1:200 IP 1:50 FC 1:50 |
理論分子量 | 21kDa |
細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | A synthesized peptide derived from human Bax |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | |
緩 沖 液 | pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Bax is a key component for cellμLar induced apoptosis through mitochondrial stress. Upon apoptoticstimμLation, Bax forms oligomers and translocates from the cytosol to the mitochondrial membrane. Throughinteractions with pore proteins on the mitochondrial membrane, Bax increases the membrane's permeability,which leads to the release of cytochrome c from mitochondria, activation of caspase-9 and initiation of thecaspase activation pathway for apoptosis
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