規(guī)格：50 μL/100 μL
貨號：PN0153
價格：1350元/50 μL、2200元/100 μL
抗體來源 | Rabbit |
克隆類型 | Monoclonal |
交叉反應(yīng) | Human |
產(chǎn)品應(yīng)用 | WB: 1:1000-1:2000 ICC/IF: 1:50-1:200 FC: 1:20-1:100 |
理論分子量 | 22kDa |
細胞定位 | Cytoplasm,Inflammasome, Endoplasmic reticμLum, Mitochondrion, Nucleus |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | A synthesized peptide derived from human ASC |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | |
緩 沖 液 | pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Functions as a key mediator in apoptosis and inflammation.Promotes caspase-mediated apoptosis involving predominantly caspase-8 and also caspase-9 in a probable cell type-specific manner.Involved in activation of the mitochondrial apoptotic pathway, promotes caspase-8-dependent proteolytic maturation of BID independently of FADD in certain cell types and also mediates mitochondrial translocation of BAX and activates BAX-dependent apoptosis coupled to activation of caspase-9, -2 and -3.
Copyright ?2023武漢皮諾飛生物科技有限公司版權(quán)所有 備案號：鄂ICP備2021001869號-1
技術(shù)支持：易暢客營銷系統(tǒng) 
