規(guī)格：50μL/100μL
貨號：PN0142
價(jià)格：1350元/50μL；2200元/100 μL
全稱 | Amyloid-beta precursor protein |
別名 | ABPP, APP, N-APP, Soluble APP-alpha, S-APP-alpha, C99, APP-C99, Abeta42, Abeta40, Beta-APP40, C83, APP-C59, Amyloid intracellμLar domain 59, APP-C57, Gamma-CTF(50), C31, App, Aβ40, Aβ42, A beta 40，beta Amyloid 40 |
抗體來源/類型 | Rabbit Polyclonal |
交叉反應(yīng) | Mouse,,Rat |
產(chǎn)品應(yīng)用 | IHC/IF：1;400-1:1000 |
理論分子量 | 86kDa |
細(xì)胞定位 | 細(xì)胞膜，細(xì)胞質(zhì) |
性 狀 | Liquid |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse Aβ40 |
亞 型 | IgG |
純化方法 | Affinity purification |
Uniprot ID | P12023 |
緩 沖 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存條件 | Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Most of autosomal dominant familial AD can be attributed to mutations in one of three genes: those encoding amyloid precursor protein (APP) and presenilins 1 and 2 Most mutations in the APP and presenilin genes increase the production of a small protein called Aβ42, which is the main component of senile plaques. Some of the mutations merely alter the ratio between Aβ42 and the other major forms—particμLarly Aβ40—without increasing Aβ42 levels.
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