規(guī)格:50μL/100μL
貨號:PN0127
價格:1350元/50μL;2200元/100 μL
全稱 | CD86 Antibody |
別名 | CD86;B7-2;B70;CD28LG2;LAB72;MGC34413; CTLA4 counter receptor B72; CLS1; Ly58; MB7; |
抗體來源 | Rabbit |
克隆類型 | Monoclonal |
交叉反應(yīng) | Mouse, Rat, Human |
產(chǎn)品應(yīng)用 | WB 1:1000~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200 IP 1:50 FC 1:50 |
理論分子量 | 38/70kDa |
細胞定位 | 細胞膜 |
性 狀 | Liquid |
濃 度 | 批次間有差異 |
免 疫 原 | A synthesized peptide derived from human CD86 |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | |
緩 沖 液 | pH: 7.2,Preservative: 0.01% Sodium azide,Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存條件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Receptor involved in the costimμLatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimμLation of naive T-cells, such as deciding between immunity and anergy that is made by T-cells within 24 hours after activation. Isoform 2 interferes with the formation of CD86 clusters, and thus acts as a negative regμLator of T-cell activation.