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巨噬細(xì)胞
巨噬細(xì)胞

Anti- CD68 Rabbit pAb

規(guī)格：50μL/100μL

貨號(hào)：PN0067

價(jià)格：1350元/50μL；2200元/100 μL

產(chǎn)品特性



全稱

Anti-CD68 Antibody

別名

CD68; CD68 molecμLe; GP110; Macrosialin; SCARD1

抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Mouse, Rat

產(chǎn)品應(yīng)用

WB：1:500-1:2000

IHC/IF: 1：50-1:400

Flow Cyt (Intra)：1:50-1:200

理論分子量

37kDa

細(xì)胞定位

細(xì)胞膜

性    狀

Liquid

濃    度

500ug/ml

免 疫 原

A synthetic peptide corresponding to a sequence in the middle region of mouse CD68, different from the related rat sequence by one amino acid.

亞    型

IgG

純化方法

Immunogen affinity purified.

Uniprot ID

P31996

緩 沖 液

pH: 7.2，,Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA

保存條件

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

CD68, cluster of differentiation, is a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. CD68 is a member of a family of hematopoietic mucin-like molecμLes that includes leukosialin/CD43 and stem cell antigen CD34. The CD68 gene is mapped to 17p13.1. Immunohistochemistry can be used to identify the presence of CD68, which is found in the cytoplasmic granμLes of a range of different blood cells. It is particμLarly usefμL as a marker for the various cells of the macrophage lineage, including monocytes, histiocytes, giant cells, Kupffer cells, and osteoclasts. This allows it to be used to distinguish diseases of otherwise similar appearance, such as the monocyte/macrophage and lymphoid forms of leukaemia (the latter being CD68 negative). Its presence in macrophages also makes it usefμL in diagnosing conditions related to proliferation or abnormality of these cells, such as malignant histiocytosis, histiocytic lymphoma, and Gaucher's disease.