規(guī)格：50μL/100μL
貨號：PN0217
價格：1350元/50μL；2200元/100 μL
全稱 | 8-OHdG (DNA/RNA Damage) |
別名 | 8-hydroxy-2'-deoxyguanosine; 2'-Deoxy-8-oxoguanosine; 7, 8-Dihydro-8-oxo-2'-deoxyguanosine; 8-Oxo-7, 8-dihydro-2'-deoxyguanosine; 8-Oxo-7, 8-dihydrodeoxyguanosine; 2'-Deoxy-8-oxo-D-guanosine; 8-Oxo-7, 8-dihydro-2μ-deoxyguanosine, 8-Oxo-dG; 2'-Deoxy-8-hydroxyguanosine; |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Rat, Species independent |
產(chǎn)品應(yīng)用 | IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
理論/實際分子量 | 0.283 kDa |
細(xì)胞定位 | 細(xì)胞質(zhì) |
性 狀 | Liquid |
濃 度 | 1mg/ml |
免 疫 原 | KLH conjugated 8-OHdG |
亞 型 | IgG |
純化方法 | affinity purified by Protein A |
緩 沖 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
8-Hydroxydeoxyguanosine (8OHdG) is a modified base that occurs in DNA due to attack by hydroxyl radicals that are formed as byproducts and intermediates of aerobic metabolism and during oxidative stress. There is increasing evidence to support the involvement of free radical reactions in the damage of biomolecμLes that eventually lead to several diseases in humans, such as atherosclerosis, cerebral and heart ischemia-reperfusion injury, cancer, rheumatoid arthritis, inflammation, diabetes, aging, and neurodegenerative conditions, such as Alzheimer's disease.
Copyright ?2023武漢皮諾飛生物科技有限公司版權(quán)所有 備案號：鄂ICP備2021001869號-1
技術(shù)支持：易暢客營銷系統(tǒng) 
