規(guī)格:50μL/100μL
貨號:PN0065
價(jià)格:1350元/50 μL ,2000元/100 μL
全稱 | Phospho-Akt(Ser473) Antibody |
別名 | AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha; |
抗體來源 | Rabbit Monoclonal |
交叉反應(yīng) | Human, Mouse,, Rat |
產(chǎn)品應(yīng)用 | WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:100~1:500 |
理論分子量 | 60kDa |
細(xì)胞定位 | 細(xì)胞質(zhì),細(xì)胞核,細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | A synthesized peptide derived from human Phospho-Akt(Ser473) |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | |
緩 沖 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存條件 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.