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信號通路
信號通路

Anti-Phospho-Akt(Ser473) Rabbit mAb

規(guī)格:50μL/100μL

貨號:PN0065

價(jià)格:1350元/50 μL ,2000元/100 μL

產(chǎn)品特性



全稱

Phospho-Akt(Ser473) Antibody

別名

AKT; AKT1 kinase; C-AKT; PKB; PKB-alpha; Protein kinase B; RAC; RAC-PK-alpha;

抗體來源

Rabbit Monoclonal

交叉反應(yīng)

Human, Mouse,, Rat

產(chǎn)品應(yīng)用

WB 1:500~1:2000

IHC 1:50~1:200

ICC/IF 1:100~1:500 

理論分子量

60kDa

細(xì)胞定位

細(xì)胞質(zhì),細(xì)胞核,細(xì)胞膜

性    狀

Liquid

濃    度


免 疫 原

A synthesized peptide derived from human Phospho-Akt(Ser473)

亞    型

IgG

純化方法

Affinity-chromatography

Uniprot ID

P31749

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

背景


An AGC kinase that plays a critical role in controlling the balance between survival and AP0ptosis. Phosphorylated and activated by PDK1 in the PI3 kinase pathway. Mediates survival signals downstream of PI3 kinase and several growth factor receptors by phosphorylating AP0pototic proteins. First found in a mouse transforming retrovirus.