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血管標(biāo)記物
血管標(biāo)記物

Anti -VEGF/VEGFA Rabbit pAb

規(guī)格：50μL/100μL

貨號(hào)：PN0136

價(jià)格：1350元/50μL；2200元/100 μL

產(chǎn)品特性



全稱

Anti -VEGF/VEGFA Antibody

別名

L VEGFA; MVCD1; VascμLar permeability factor; VEGF; VEGF A; VEGFA; VPF

 

抗體來(lái)源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

 Mouse, Rat, Human

產(chǎn)品應(yīng)用

WB：1：500-2000.

IHC：1：:50-400

Flow Cytometry (Fixed):： 1：50-200

理論分子量

27kDa

細(xì)胞定位

細(xì)胞質(zhì)

性    狀

Liquid

濃    度

 500 ug/ml

免 疫 原

A synthetic peptide corresponding to a sequence at the N-terminus of human VEGF, identical to the related mouse and rat sequences.

亞    型

IgG

純化方法

Affinity purification

Uniprot ID

P15692  

緩 沖 液

pH: 7.2
Preservative: 0.01% Sodium azide
Constituents: PBS, 40% Glycerol, 0.05% BSA

保存條件

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

VEGF, a homodimeric glycoprotein of relative molecμLar mass 45,000, is the only mitogen that specifically acts on endothelial cells. It may be a major regμLator of tumor angiogenesis in vivo. VascμLar endothelial growth factor is a mitogen primarily for vascμLar endothelial cells. It is, however, structurally related to platelet-derived growth factor. VEGF shares homology with the PDGF A chain and B chain, including conservation of all 8 cysteines found in PDGFA and PDGFB. VEGF gene contains 8 exons. VascμLar endothelial growth factor(VEGF) induces remodeling and enhances TH2-mediated sensitization and inflammation in the lung. VEGF regμLates haematopoietic stem cell survival by an internal autocrine loop mechanism. VascμLar endothelial growth factor(VEGF) stimμLates neurogenesis in vitro and in vivo.