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細(xì)胞粘附與腫瘤侵襲與轉(zhuǎn)移
細(xì)胞粘附與腫瘤侵襲與轉(zhuǎn)移

Anti N-cadherin Rabbit pAb

規(guī)格：50μL/100μL

貨號(hào)：PN0138

價(jià)格：1350元/50μL；2200元/100 μL

產(chǎn)品特性



全稱

Cadherin-2

別名

CDH2, CD325, CDHN, CDw325, NCAD, cadherin 2

抗體來源/類型

Rabbit Polyclonal

交叉反應(yīng)

Human, Mouse, Rat

產(chǎn)品應(yīng)用

WB： 1:500-1：1000

IHC/IF  : 1:400-1:1600

理論分子量

100kDa

細(xì)胞定位

細(xì)胞膜，細(xì)胞連接，細(xì)胞表面

性    狀

Liquid

濃    度


免 疫 原

KLH conjugated Synthetic peptide corresponding to Mouse N-cadherin

亞    型

IgG

純化方法

Antigen affinity purification

Uniprot ID

P19022

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

背景

Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regμLator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adμLt subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modμLate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regμLate dendritic spine density.