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細(xì)胞因子
細(xì)胞因子

Anti -TNF- alpha Rabbit pAb

規(guī)格:50μL/100μL

貨號(hào):PN0118

價(jià)格:1350元/50μL,2200元/100 μL

產(chǎn)品特性



全稱

Tumor necrosis factor alpha

別名

TNF,DIF,TNF-alpha,TNFA,TNFSF2,Tumour necrosis factor, Tumour necrosis factor alpha,tumor necrosis factor, TNLG1, TNF-α, TNF a, TNF alpha,NFα, TNF-α, Cachectin, TNFα.

 

抗體來源

Rabbit

克隆類型

Polyclonal

交叉反應(yīng)

Mouse, Rat

產(chǎn)品應(yīng)用

WB:   1: 200-1: 500IHC/IF:  1: 200-1: 800

 

理論分子量

26kDa

細(xì)胞定位

細(xì)胞膜,分泌型蛋白

性    狀

Liquid

濃    度

批次間有差異

免 疫 原

KLH conjugated Synthetic peptide corresponding to Mouse TNF-alpha

亞    型

IgG

純化方法

Affinity purification

Uniprot ID

P01375

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

TNF, as also known as TNF-alpha, or cachectin, is a mμLtifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. It is expressed as a 26 kDa membrane bound protein and is then cleaved by TNF-alpha converting enzyme (TACE) to release the soluble 17 kDa monomer, which forms homotrimers in circμLation. It is produced chiefly by activated macrophages, although it can be produced by many other cell types such as CD4+ lymphocytes, NK cells, neutrophils, mast cells, eosinophils, and neurons. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR.