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細(xì)胞因子
細(xì)胞因子

Anti -IL-2 Receptor alpha Rabbit pAb

規(guī)格：50μL/100μL

貨號(hào)：PN0117

價(jià)格：1350元/50μL，2200元/100 μL

產(chǎn)品特性



全稱

IL-2 Receptor alpha rabbit polyclonal antibody

別名

IL2RA, CD25, IDDM10, IL2R, TCGFR, p55, IMD41, interleukin 2 receptor subunit alpha

 

抗體來源

Rabbit  

克隆類型

Polyclonal

交叉反應(yīng)

mouse，Rat

產(chǎn)品應(yīng)用

WB=1:500-1000,

IHC/IF=1:200-1000,

理論分子量

31kDa

細(xì)胞定位

細(xì)胞膜

性    狀

Liquid

濃    度

批次間有差異

免 疫 原

KLH conjugated Synthetic peptide corresponding to Mouse IL2RA

亞    型

IgG

純化方法

Affinity purification

Uniprot ID

P01590

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

IL-2Rα(Activated T cells IL-2Rα Chain 55), also kown as membrane interleukin-2 receptor (mIL-2R) or CD25, is a protein encoded by IL2RA gene in Human. This protein is 55 kDa which is the high affinity composition of IL-2R. Few IL-2α chains will express in inactive T cells, while the expression will remarkably increase followed by IL-2 accumμLation, when T cell surface receptor (TCR) is active. IL-2αchains will become soluble interleukin-2 receptor (sIL-2R) when they are detached from cell membrane into serum, and the molecμLar weight of sIL-2R is 45 kDa. The concentration of sIL-2R in serum can be used for a mark to measure T cells activation and IL-2Rα chains expression.