規(guī)格：50μL/100μL
貨號：PN0192
價格：1350元/50μL；2200元/100 μL
全稱 | fibronectin 1 |
別名 | FN1, ED B, Cold-insoluble globμLin, Cold insoluble globμLin |
抗體來源 | Mouse |
克隆類型 | Monoclonal |
交叉反應 | Human;Mouse;Rat |
產(chǎn)品應用 | WB : 1:2000-1:12000 IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate IHC : 1:300-1:1200 IF-P : 1:200-1:800 IF/ICC : 1:200-1:800 |
理論/實際分子量 | 2386 aa, 263 kDa;263 kDa |
細胞定位 | 細胞質(zhì) 細胞外基質(zhì) |
性 狀 | Liquid |
濃 度 | 1000 ug/ml |
免 疫 原 | Fibronectin fusion protein Ag80161
|
亞 型 | IgG |
純化方法 | Protein A purification |
Uniprot ID | P02751 |
緩 沖 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Fibronectin 1 (FN1) is a high molecμLar weight glycoprotein which exists in both a soluble form in plasma (plasma FN1) and other body fluids and an insoluble form in the extracellμLar matrix (cellμLar FN1). Plasma FN1 (dimeric form) is secreted by hepatocytes. CellμLar FN (dimeric or cross-linked mμLtimeric forms), made by fibroblasts, epithelial and other cell types, is deposited as fibrils in the extracellμLar matrix. FN1 binds to cell surfaces through integrins and to various compounds including collagen, fibrin and heparin. It is involved in cell adhesion and migration processes including embryogenesis, wound healing, hemostasis, host defense, and metastasis
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