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鐵死亡
鐵死亡

Anti-GPX4 Mouse mAb

規(guī)格:50μL/100μL

貨號(hào):PN00742

價(jià)格:1350/50μL;2200元/100 μL

產(chǎn)品特性




全稱

glutathione peroxidase 4 (phospholipid hydroperoxidase)

別名

GSHPx 4, GPx-4, GPx 4, EC:1.11.1.9, EC:1.11.1.12

抗體來(lái)源

Mouse

克隆類型

Monoclonal

交叉反應(yīng)

Human, Mouse, Rat, Pig, Rabbit, Chicken, Zebrafish, Hamster, Dog

 (predicted:Human, Mouse, Rat, Pig, Chicken, Bovine, Goat, Sheep, Duck)

產(chǎn)品應(yīng)用

WB : 1:1000-1:4000 

IHC : 1:1000-1:4000

IF/ICC : 1:400-1:1600

理論分子量

20-23kDa

細(xì)胞定位

細(xì)胞質(zhì) 線粒體

性    狀

Liquid

濃    度

1000ug/ml

免 疫 原

GPX4 fusion protein Ag30650 

亞    型

IgG

純化方法

Protein A purification

Uniprot ID

P36969

緩 沖 液

 PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

 

背景

GPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about 20KDa and 22KDa, respectively. GPX4 is a monomer,but it has a tendency to form higher mass oligomers (PMID:17630701). It presents primarily in testis.