規(guī)格:50μL/100μL
貨號(hào):PN00742
價(jià)格:1350/50μL;2200元/100 μL
全稱 | glutathione peroxidase 4 (phospholipid hydroperoxidase) |
別名 | GSHPx 4, GPx-4, GPx 4, EC:1.11.1.9, EC:1.11.1.12 |
抗體來(lái)源 | Mouse |
克隆類型 | Monoclonal |
交叉反應(yīng) | Human, Mouse, Rat, Pig, Rabbit, Chicken, Zebrafish, Hamster, Dog (predicted:Human, Mouse, Rat, Pig, Chicken, Bovine, Goat, Sheep, Duck) |
產(chǎn)品應(yīng)用 | WB : 1:1000-1:4000 IHC : 1:1000-1:4000 IF/ICC : 1:400-1:1600 |
理論分子量 | 20-23kDa |
細(xì)胞定位 | 細(xì)胞質(zhì) 線粒體 |
性 狀 | Liquid |
濃 度 | 1000ug/ml |
免 疫 原 | GPX4 fusion protein Ag30650 |
亞 型 | IgG |
純化方法 | Protein A purification |
Uniprot ID | |
緩 沖 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存條件 | Store at -20°C. Stable for one year after shipment. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
GPX4 (Phospholipid hydroperoxide glutathione peroxidase, mitochondrial) protects cells against membrane lipid peroxidation and cell death. Required for normal sperm development and male fertility.It has two isforms about 20KDa and 22KDa, respectively. GPX4 is a monomer,but it has a tendency to form higher mass oligomers (PMID:17630701). It presents primarily in testis.