規(guī)格：50μL/100μL
貨號：PN0187
價格：1350元/50μL；2200元/100 μL
全稱 | Tyrosine 3-monooxygenase |
別名 | TH, Th, DYT14, DYT5b, TYH, tyrosine hydroxylase, Tyrosine hydroxy |
抗體來源/類型 | Rabbit Polyclonal |
交叉反應 | Human, Mouse, Rat, Monkey |
產品應用 | WB：1：500-1000 IHC：1：500-2000 IF： 1：500-2000 |
理論分子量 | 62kDa |
細胞定位 | 細胞質，軸突 |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | Recombinant protein corresponding to Mouse Tyrosine Hydroxylase
|
亞 型 | IgG |
純化方法 | Affinity purification |
Uniprot ID | P24529 |
緩 沖 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存條件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
Tyrosine hydroxylase or tyrosine 3-monooxygenase is the enzyme responsible for catalyzing the conversion of the amino acid L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA). It does so using molecμLar oxygen(O2), as well as iron (Fe2+) and tetrahydrobiopterin as cofactors. L-DOPA is a precursor for dopamine, which, in turn, is a precursor for the important neurotransmitters norepinephrine (noradrenaline) and epinephrine(adrenaline). Tyrosine hydroxylase catalyzes the rate limiting step in this synthesis of catecholamines.
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