規(guī)格：50μL/100μL
貨號(hào)：PN0164
價(jià)格：1350元/50μL；2200元/100 μL
全稱 | MicrotubμLe-associated protein 2 |
別名 | MAP2, MAP2A, MAP2B, MAP2C, microtubμLe associated protein 2
|
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Mouse;Rat |
產(chǎn)品應(yīng)用 | IHC 1:500-1:3000 ICC/IF 1:500-1:3000 |
理論/預(yù)測分子量 | 200kDa/70, 280 kDa |
細(xì)胞定位 | 細(xì)胞質(zhì)，細(xì)胞骨架，細(xì)胞突起 |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to Mouse MAP2 |
亞 型 | IgG |
純化方法 | Affinity purification |
Uniprot ID | |
緩 沖 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存條件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
The proteins of this family are thought to be involved in microtubμLe assembly, which is an essential step in neuritogenesis. MAP2 serves to stabilize microtubμLes (MT) growth by crosslinking MT with intermediate filaments and other MTs. The products of similar genes in rat and mouse are neuron-specific cytoskeletal proteins that are enriched in dendrites, implicating a role in determining and stabilizing dendritic shape during neuron development. A number of alternatively spliced variants encoding distinct isoforms have been described.
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