規(guī)格：50μL/100μL
貨號：PN0063
價格：1350元/50 μL , 2200元/100 μL
全稱 | Akt Antibody |
別名 | PKB;RAC;PRKBA;PKB-ALPHA;RAC-ALPHA; AKT1 ; AKT2; AKT3; Akt1/2/3; pan Akt; |
抗體來源 | Rabbit Monoclonal |
交叉反應 | Human;Mouse;Rat |
產品應用 | WB 1:1000-1:2000 IHC 1:100-1:200 ICC/IF 1:50-1:200 IHF 1:50-1:200 IP 1:20-1:50 FC 1:20-1:100 |
理論分子量 | 56kDa |
細胞定位 | 細胞膜，細胞質，細胞核 |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | A synthesized peptide derived from human AKT1 |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
UniProt ID | |
緩 沖 液 | PBS with 0.02% sodium azide and 50% glycerol pH 7.3. |
保存條件 | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1.
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