規(guī)格：50μL/100μL
貨號：PN0125
價格：1350元/50μL；2200元/100 μL
全稱 | CD11b Antibody |
別名 | CR3A; MO1A; CD11B; MAC-1; MAC1A; SLEB6;ITGAM |
抗體來源 | Rabbit |
克隆類型 | Monoclonal |
交叉反應(yīng) | Mouse, Rat, Human |
產(chǎn)品應(yīng)用 | WB 1:1000-1:2000 IHC 1:100-1:200 ICC/IF 1:50-1:200 IHF 1:50-1:200 |
理論分子量 | 127/170kDa |
細(xì)胞定位 | 細(xì)胞膜 |
性 狀 | Liquid |
濃 度 | 具體以批次為準(zhǔn) |
免 疫 原 | A synthesized peptide derived from human CD11b |
亞 型 | IgG |
純化方法 | Affinity-chromatography |
Uniprot ID | |
緩 沖 液 | pH: 7.2，Preservative: 0.01% Sodium azide，Constituents: PBS, 40% Glycerol, 0.05% BSA |
保存條件 | Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
ITGAM, also named as CD11B and CR3A, belongs to the integrin alpha chain family. It is implicated in various adhesive interactions of monocytes, macrophages and granμLocytes as well as in mediating the uptake of complement-coated particles. ITGAM is identical with CR-3, the receptor for the iC3b fragment of the third complement component. It probably recognizes the R-G-D peptide in C3b.
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