規(guī)格：50μL/100μL
貨號：PN0177
價格：1350元/50μL；2200元/100 μL
全稱 | Keratin, type II cytoskeletal 8 |
別名 | KRT8, CARD2, CK-8, CK8, CYK8, K2C8, K8, KO, keratin 8 |
抗體來源 | Rabbit |
克隆類型 | Polyclonal |
交叉反應(yīng) | Human, Mouse, Rat |
產(chǎn)品應(yīng)用 | WB 1:1500-1:1000 IHC/IF 1:200-1:1000 |
理論/實際分子量 | 54kDa |
細(xì)胞定位 | 細(xì)胞質(zhì) 細(xì)胞核 |
性 狀 | Liquid |
濃 度 | |
免 疫 原 | KLH conjugated Synthetic peptide corresponding to MouseCytokeratin 8
|
亞 型 | IgG |
純化方法 | Affinity purification |
Uniprot ID | |
緩 沖 液 | Rabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol. |
保存條件 | Store at +4°C for short term. Store at -20°C for long term. Avoid freeze/thaw cycle. |
注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
背景
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellμLar structural integrity and also functions in signal transduction and cellμLar differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene.
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