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白細(xì)胞抗原
白細(xì)胞抗原

Anti-CD105 Rabbit pAb

規(guī)格：50μL/100μL

貨號(hào)：PN0157

價(jià)格：1350元/50μL；2200元/100 μL

產(chǎn)品特性



全稱(chēng)

Endoglin

別名

Cell surface MJ7/18 antigen, CD105, Eng, Edg, FLJ41744, HHT1, ORW, ORW1

 

抗體來(lái)源

Rabbit polyclonal

交叉反應(yīng)

Human

產(chǎn)品應(yīng)用

IHC： 1:500~1:1000

IF：  1:500~1:1000

理論/觀測(cè)到的分子量

71 kDa / 90 kDa

細(xì)胞定位

細(xì)胞膜

性    狀

Liquid

濃    度


免 疫 原

A synthesized peptide derived from human CD105

亞    型

IgG

純化方法

Affinity purification

Uniprot ID

P17813

緩 沖 液

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

保存條件

Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20℃storage.

注意事項(xiàng)

This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

 

背景

Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disμLphide-linked subunits of 95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascμLar endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascμLar development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.